Classification Of Polypeptide Spectra From Rat Liver Samples

Lithsin Loo,John Quinn,James A Armitage,Hayley Cordingley, S L L Roberts,Peter J Bugelski,Leonid Hrebien,Moshe Kam

PROCEEDINGS OF THE IEEE 28TH ANNUAL NORTHEAST BIOENGINEERING CONFERENCE（2002）

引用 1|浏览5

暂无评分

摘要

We use clustering-based algorithms to classify polypeptide spectra of treated rat liver samples obtained through surface enhanced laser desorption/ionization mass spectrometry (SELDI-MS). Variance analysis is used to extract useful features from the high dimensional datasets. The features are then clustered using a hierarchical clustering algorithm based on scaled Euclidean distances. The clusters created are found to be correlated to the toxicity of the rat liver samples.

查看译文

关键词

hepatotoxicity, hierarchical clustering, matrix assisted laser desorption/ionization, polypeptide spectra, predictive toxicology, SELDI

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要