Minimizing Leukemia Escape: Implementing a Dual Anti-Cd20- and CD19-scFv-based Chimeric Antigen Receptor (CAR)

Dina Schneider,Ying Xiong,Andre Roy,Andrew Kaiser,Boro Dropulic,Rimas Orentas

Journal for ImmunoTherapy of Cancer（2015）

引用 2|浏览5

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摘要

Meeting abstracts Adoptive immunotherapy with chimeric antigen receptor (CAR) transduced T lymphocytes has shown promising results in both pediatric and adult B cell malignancies. Nevertheless, both CAR-based and antibody-based anti-CD19 therapies, e.g. blinatumomab, have seen treatment failures

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关键词

Flow Cytometric Analysis,Tumor Antigen,Chimeric Antigen Receptor,Adoptive Immunotherapy,CD20 Surface Marker

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