Response to influenza immunization in patients with common variable immunodeficiency

Wei Zhan,Fengyun Yue,Jun Liu,Jason K Lee,Jason Ho,Susan Moir,Mario A Ostrowski,Stephen D Betschel

Allergy, Asthma & Clinical Immunology（2011）

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摘要

Background Common variable immunodeficiency (CVID) is a heterogeneous primary immunodeficiency characterized by low serum antibody levels and recurrent infections. Cellular response to immunization in CVID has not been elucidated. In this study aimed to characterize influenza specific memory B-cell responses in patients with CVID and normal controls following influenza immunization.

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关键词

Influenza,Influenza Vaccine,Primary Immunodeficiency,Severe Defect,Specific Memory

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