ChemInform Abstract: Isolation and Structure Determination of Pycnidione, a Novel Bistropolone Stromelysin Inhibitor from a Phoma sp.

Guy H Harris, K Hoogsteen,Keith C Silverman,Susan Raghoobar,Gerald F Bills,Russell B Lingham,J L Smith, H W Dougherty,Carmen Cascales,Fernando Pelaez

Cheminform（1993）

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摘要

Abstract A novel bistropolone, pycnidione (1), was isolated by bioassay guided fractionation from fermentations of a Phoma sp.. The structure was determined by spectroscopic methods and single crystal X-ray diffraction.

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