A Personalized Adjuvant Treatment for Women over 70 Presenting with a Luminal Breast Cancer? ASTER 70s or an Ongoing Phase III Trial with Parallel Cohort by the UNICANCER GERICO and UCBG Groups for an Ongoing Question…

Purpose: Better definition of high-risk breast cancer (BC) candidates for adjuvant chemotherapy is warranted in case of oestrogen receptor-positive (ER+) HER2-negative (HER2−) phenotype, especially in elderly women in whom competing risks for overall survival (OS) increase due to ageing.