Simultaneous determinations of 17 marker compounds in Xiao–Chai–Hu–Tang by LC–MS/MS: Application to its pharmacokinetic studies in mice

Rongjin Sun,Min Zeng,Ting Du,Li Li,Guangyi Yang,Ming Hu,Song Gao

Journal of Chromatography B（2015）

引用 15|浏览7

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摘要

•An UPLC–MS/MS method to quantify 17 compounds in Xiao–Chai–Hu–Tang in blood was developed.•The sensitivity and robust method was validated.•The sensitivity and robust method was applied for pharmacokinetic study in mice.

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关键词

UPLC,I.S.,DP,CE,CXP,AUC,QC,LLOD,LLOQ,XCHT,MPA,MPB

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