Induction or consolidation chemotherapy for unresectable stage III non-small-cell lung cancer patients treated with concurrent chemoradiation: a randomised phase II trial GFPC – IFCT 02-01

P Fournel,H Lena,Radj Gervais,Herve Le Caer, Mariececile Bozonnat,Jeanpierre Daures,Jeannoel Talabard,Alain Vergnenegre, B Melloni,C Decroisette,P Clavere,G Robinet, Sophie Bayle,Jean Philippe Labat, C Belleguic,M Benchalal,A Riviere, D Lerouge,P J Souquet, L Geriniere, A Dhombres, F Mornex,H Le Caer, E Tessier, H Ramos, J M Chavaillon,C Chouaid,E Touboul,S Bota,L Thiberville, O Gallocher, E Quoix, B Mennecier, G M Jung,Lionel Falchero,D Paillotin, S Schouabe, E Jonveaux, J C Bout, Paul J Martin,Maurice Perol, D Arpin,Isabelle Martellafay, J Letreut,Roland Poirier, A Benyoub, J M Vernejoux, R Trouette,E Dansin, H Berard, Jeanclaude Pietra,G Zalcman, P Thomas, A Zribi,B Milleron, A Lavole, D Coetmeur, Bruno Lamezec, C Bonnamour, V Grangeon, J P Suchaud,Jacky Crequit, S Ramdane, P Barre, M A Zawadi,Celine Gimenez,Fabrice Barlesi, T Pignon, M Grivaux,F Blanchon, J Mandet, D Perdu, Adela Cauchois, J Y Delhoume, B Kin,Philippe Merle, H Janicot, Pierre Verrelle,J B Auliac, Y Coscas, A Ducolone, David J Herman, A Roquette

European Journal of Cancer（2016）

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摘要

•Optimal sequencing of radiotherapy and chemotherapy is not well defined for stage III NSCLC.•Cisplatin-based chemotherapy as induction or consolidation of chemoradiotherapy is safe.•Response rates were similar in both arms without difference in survival.

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关键词

Lung cancer,Radiotherapy,Chemotherapy,Therapeutics

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