Rb006, A Direct Factor Ix Inhibitor Results In Consistent And Near Complete Inhibition Of Factor Ix In Patients With Acute Coronary Syndromes: A Radar Pharmacokinetic And Pharmacodynamic Substudy

Thomas J. Povsic,William A. Wargin,Mauricio G. Cohen,Roxana Mehran,Christoph Bode, Joshua Krasnow,Merill Krolick,Christopher P. Rusconi,Steven L. Zelenkofske,Richard A. Becker,John H. Alexander

Circulation（2010）

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摘要

Background: The REG1 system consists of RB006, a direct FIXa inhibitor, and RB007, its active control agent. RB006 produces consistent and near complete inhibition of factor IXa in healthy controls...

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关键词

Anticoagulants, Acute coronary syndromes, Percutaneous coronary intervention, Anticoagulation, Pharmacokinetics

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