Abstract 12010: Physiological Overexpression of PGC-1alpha Preserves Mitochondrial Function and Reduces Fibrosis but Does Not Prevent Cardiac Dysfunction Following Pressure Overload Hypertrophy

Renata O Pereira,Ashley Crum,Adam R Wende,Curtis Olsen,E Dale Abel

Circulation（2011）

引用 23|浏览4

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摘要

Peroxisome proliferator-activated receptor coactivator-1 alpha (PGC-1α) is an inducible integrator of transcriptional circuits that regulate mitochondrial biogenesis and function. In physiological ...

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关键词

Mitochondria, Hypertrophy, Metabolism, Transgenic models

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