谷歌浏览器插件
订阅小程序
在清言上使用

PWE-029 Objective Assessment of Physical Activity As a Measure of Functional Recovery and Quality of Life Following Oesophago-Gastric Cancer Resection

Gut(2012)

引用 1|浏览8
暂无评分
摘要
Introduction Functional recovery following surgery is determined by the interaction between pre-operative performance, post-operative catabolism, nutritional status, and mood. Physical activity (PA) is an important domain of health-related quality-of-life (HRQL), and may be a useful objective index of recovery. We aimed to use an accelerometer-based activity metre (ActivPAL) to monitor post-operative PA in oesophago-gastric (OG) cancer patients undergoing surgery with curative intent. Methods PA measures, including step count, time spent in various body positions, and energy expenditure of activity, were assessed over 7-day periods in patients undergoing oesophagectomy or gastrectomy (n=16). Nutritional status, HRQL (FAACT, FACIT-F and EORTC-QLQC30 questionnaires), and mood (HADS questionnaire) were also assessed. Time-points were pre-operatively and 1–2 weeks, 5–6 weeks, 3 months and 6 months post-operatively. Results Compared with pre-operative results, PA measures were decreased by 23–89% (p<0.05) 1–2 weeks post-operatively, and were still decreased by 15–57% (p<0.05) 5–6 weeks post-operatively. At 3 months, all PA measures except time spent upright (p=0.009) and time spent standing (p=0.013) had recovered. Measures of PA correlated positively with physical and functional domains of HRQL, including EORTC-QLQ30 Global Health Status, FAACT Trial Outcome Index (TOI) and FACIT-TOI (p<0.001), and inversely with HADS-Depression (p<0.001). Conclusion There is marked impairment of PA at the time of hospital discharge and a gradual recovery over 3–6 months. This carries significant implications in a disease where surgical patients may survive <2 years. PA measures are suitable outcomes for evaluating the impact of enhanced recovery programmes on functional recovery and HRQL. Competing interests None declared.
更多
查看译文
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要