Need For Recurrent Resection And Complex Phenotype Are Associated With A Specific Antibody Signature In Crohn'S Disease Patients Undergoing Resection; Smoking Is Not Associated With Prevalent Antibodies; Prognostic And Mechanistic Implications

tions of IBD, i.e. flare or surgery occurring within 1 to 4 months of US, was calculated. Endoscopic and MRE findings were categorized for each bowel segment and the agreement between US and other techniques was considered only if the agreement on presence of disease activity was achieved for all segments. Results: In total, 80 US were performed in 79 patients; 62 (78%) with Crohn`s disease, 16 (20%) with ulcerative colitis, 1 pts with IBD unclassified; 52 (65%) women; mean age 35 years, range 19-79. Overall, there were 44 (55%) cases of US findings of active disease, in 6 patients fistula or abscess were found on US. From 36 cases with negative US findings, 35 were in remission without any changes in therapy at the median follow-up of 3 months (range 1 to 5 month); resulting in negative predictive value of 97% (95%CI 85.42 % to 99.54 %). During the follow-up period, 32 (40%) patients underwent MRE and 21 (26%) ileocolonoscopy, with agreement of US findings in 84% and 73% of cases for MRE and ileocolonoscopy, respectively. Conclusions: Transabdominal ultrasound has high negative predictive value for short-term complications of inflammatory bowel disease and seems to be a promising tool for rapid and non-invasive triage of IBD patients who do not necessitate further diagnostic work-up.