O-085 Dietary Protein In The Very-low-birth-weight Infant: Multicenter Randomised Controlled Trial To Evaluate The Effects Of Dietary Protein Level On Growth
Archives of Disease in Childhood(2014)
摘要
Background Several studies suggest that formulas with protein content of 3.0 g/100 kcal do not fully meet the protein needs of preterm very-low-birth-weight infants (VLBWI). This study compared growth, protein-energy status and metabolic status in VLBWI fed either a standard- (Std-Pro: 3.0 g/100 kcal) or high- (Hi-Pro: 3.6 g/100 kcal) protein infant formula. Methods Once enteral feeding tolerance was established, infants were randomised to be fed either Std-Pro or Hi-Pro formula for a minimum period of 3 weeks. Dietary intake, serum chemistries and growth were closely monitored during the study. Data were analysed on an intention-to-treat basis using a combination of linear mixed model and ANOVA. Results were considered significant at p Results Sixty-nine infants were enrolled, 51 completed the study. No differences were detected in demographics or energy intakes but protein intake was greater in infants fed Hi-Pro (mean difference: +0.7 g/kg/day, p Conclusion A dietary protein intake of 3.6 g/100 kcal meets energy and protein needs while an intake of 3.0 g/100 kcal meets energy but not protein needs in rapidly growing preterm VLBWI.
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