Comparison of feature tracking and harmonic phase imaging for strain measurement on cardiovascular magnetic resonance in pediatric cancer survivors

Background Pediatric cancer survivors after anthracycline therapy are at risk for left ventricular systolic dysfunction. Strain may be a more sensitive marker than left ventricular ejection fraction (LVEF). Feature tracking (FT) is a promising technique for strain measurement on cardiovascular magnetic resonance (CMR) images, but has limited validation vs. the gold standard of harmonic phase (HARP) imaging analysis. This study aimed to compare strain by FT and HARP on CMR images in pediatric cancer survivors.