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MP85-17 IS PATIENT'S BMI A DETERMINANT OF MORBIDITY IN RENAL TRANSPLANTATION?

˜The œJournal of urology/˜The œjournal of urology(2015)

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You have accessJournal of UrologyTransplantation & Vascular Surgery: Renal Transplantation & Vascular Surgery II1 Apr 2015MP85-17 IS PATIENT'S BMI A DETERMINANT OF MORBIDITY IN RENAL TRANSPLANTATION? Vanessa Queruel, Rémi Kabore, Adeline Guillaume, Karine Moreau, Karen Leffondre, Lionel Couzi, Pierre Merville, Alice Quinart, Julien Rogier, Patrick Tauzin-Fin, Jean-Marie Ferriere, and Jean-Christophe Bernhard Vanessa QueruelVanessa Queruel More articles by this author , Rémi KaboreRémi Kabore More articles by this author , Adeline GuillaumeAdeline Guillaume More articles by this author , Karine MoreauKarine Moreau More articles by this author , Karen LeffondreKaren Leffondre More articles by this author , Lionel CouziLionel Couzi More articles by this author , Pierre MervillePierre Merville More articles by this author , Alice QuinartAlice Quinart More articles by this author , Julien RogierJulien Rogier More articles by this author , Patrick Tauzin-FinPatrick Tauzin-Fin More articles by this author , Jean-Marie FerriereJean-Marie Ferriere More articles by this author , and Jean-Christophe BernhardJean-Christophe Bernhard More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.1871AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES General surgical believe is that obesity increases the difficulty of surgery. Overweight prevalence has been increasing over the past 20 years and kidney transplant recipients seem to have the same evolution than general population. The aim of this study was to assess the impact of the Body Mass Index (BMI) on peri and postoperative morbidity. METHODS All kidney transplant cases performed from January 2006 to December 2011 in a single center were retrospectively analyzed. The data regarding patients' characteristics, surgery procedure, per and post-operative complications and renal function were collected. The patients were divided into 4 groups based on their BMI: underweight (BMI<18.5), normal weight (18.530). The groups' characteristics were compared using Chi square, Fisher's exact or Wilcoxon tests. The association between BMI and complications was assessed by univariate and multivariable logistic regression modeling. RESULTS A total number of 694 cases were included, 464 were males. Mean age was 50.7+/-13. Of the 694, 360 patients (51.87%) had a normal body mass index, 51 (7.35%) were underweight, 218 (31.41%) were overweight and 65 (9.37%) were obese. Mean surgery time was 157 minutes; mean postoperative length of stay was 17 days. After surgery, 195 (28.15%) suffered from postoperative sepsis, 218 (32%) had a delayed graft function, 30 (4.4%) developed parietal hematoma and 80 (12%) a wound dehiscence. In multivariable analysis, obesity was significantly associated with an increased risk of per-operative blood loss with a mean delta of 88,34 mL (95%CI [9.05-168]). Parietal complications such as haematoma (OR 3.35; 95%CI [1.02-11.03]), and wound dehiscence (OR 4.18; 95%CI [1.83-9.56]) were also significantly increased in case of obesity. Overweight patients showed a higher incidence of delayed graft function (OR 1.51 95%CI: [1.00-2.27]) and the operative time was, in average, 9.26min longer (95%CI [2.00-16.52]). Underweight was a risk factor for postoperative sepsis (OR 2.65; 95%CI [1.33-5.27]). No significant difference was found regarding urinary complications, lymphocele, wound infection, postoperative length of stay, acute or chronic graft rejection. CONCLUSIONS In our experience, patient's BMI impacts peri and post-operative outcomes. BMI>25 significantly increased the risk of surgical complications (blood loss, length of surgery, parietal complications) whereas a BMI<18.5 was an independent risk factor for sepsis. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e1073 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Vanessa Queruel More articles by this author Rémi Kabore More articles by this author Adeline Guillaume More articles by this author Karine Moreau More articles by this author Karen Leffondre More articles by this author Lionel Couzi More articles by this author Pierre Merville More articles by this author Alice Quinart More articles by this author Julien Rogier More articles by this author Patrick Tauzin-Fin More articles by this author Jean-Marie Ferriere More articles by this author Jean-Christophe Bernhard More articles by this author Expand All Advertisement Advertisement PDF DownloadLoading ...
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