MP9-20 BASELINE CLINICAL CARACHTERISTICS AND PATHOLOGICAL OUTCOMES FOLLOWING ROBOTIC-ASSISTED LAPAROSCOPIC RADICAL PROSTATECTOMY (RALP): A POPULATION BASED PROSPECTIVE SERIES.

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Evidence-based Medicine & Outcomes II1 Apr 2015MP9-20 BASELINE CLINICAL CARACHTERISTICS AND PATHOLOGICAL OUTCOMES FOLLOWING ROBOTIC-ASSISTED LAPAROSCOPIC RADICAL PROSTATECTOMY (RALP): A POPULATION BASED PROSPECTIVE SERIES. Lorenzo Tosco, Filip Ameye, Simone Albisinni, Peter Dekuyper, David Jegou, Thierry Quackels, Thierry Roumeguere, Ben Van Cleynenbreugel, Nancy Van Damme, Liesbet Van Eycken, and Steven Joniau Lorenzo ToscoLorenzo Tosco More articles by this author , Filip AmeyeFilip Ameye More articles by this author , Simone AlbisinniSimone Albisinni More articles by this author , Peter DekuyperPeter Dekuyper More articles by this author , David JegouDavid Jegou More articles by this author , Thierry QuackelsThierry Quackels More articles by this author , Thierry RoumeguereThierry Roumeguere More articles by this author , Ben Van CleynenbreugelBen Van Cleynenbreugel More articles by this author , Nancy Van DammeNancy Van Damme More articles by this author , Liesbet Van EyckenLiesbet Van Eycken More articles by this author , and Steven JoniauSteven Joniau More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.380AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Since robotic surgery has been implemented in the urological field many series have published, the majority of which are single-center retrospective case series. The aim of this study is to present a prospective nation-wide series of robotic assisted laparoscopic radical prostatectomy (RALP) and to describe baseline clinical characteristics and pathological outcomes. METHODS Since September 2009, a nation-wide prospective RALP registration has been implemented. Until July 2014, 6032 RALP cases were registered in 24 urological centers with a median number of 187 cases (IQR 84–323) per center. Pre- and postoperative clinico-pathological features, nerve sparing approach, performance of lymph node dissection and peri-postoperative complications are described. RESULTS Mean age was 63.1 years (range 34–84). Median PSA was 6.3 ng/ml (IQR 4.5-9-2). 94.2% (n=5863) of prostate cancers were staged as cT1-2 and 4.6 % (n=275) as cT3. The majority of biopsy Gleason score (bGS) consisted of bGS 6, 45.7% (n=2,757) and bGS7, 29.5% (n=1,781); while 8.9% (n=535) biopsies showed GS8-10. bG8 increased from 5% to 8.8% and bGS9 from 2.1 to 3.8% respectively from 2009 to 2014. The same increasing trend was observed for iPSA≥20ng/mL which passed from 4.1% at the beginning of the registration to 5.9% in 2014.69.1% (n=4169) of the procedures were performed with nerve-sparing technique of which the majority (68.8%) underwent bilateral nerve-sparing surgery. In 70.7%, lymph node dissection was not performed. However, there was a positive trend in PLND uptake over time, ranging from 21.3% in 2009 to 35% in 2014. Intraoperative complications were observed in 2.7% of cases (n=165); in these, a conversion rate of 7.3% (12 cases) mostly for hemorrhagic complications. Pathological stage was pT2 in 71.4% (n=4307), pT3a 18.4% (n=1108), pT3b 8.6% (n=519) and pT4 in 0.9% of cases. 88.5% of pathological Gleason score were pGS<8, and 11.5% pGS8-10. Positive surgical margins (PSM) were observed in 23.6% of cases and they increased from 23.5% to 27.0% during the registration period; PSM increased in parallel with pTstage. CONCLUSIONS The majority of cases in this population based study were cT1-2, cGS 6–7 disease treated by nerve sparing surgery and limited use of lymph node dissection. An increased trend to more clinically aggressive disease during last years was observed. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e109 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Lorenzo Tosco More articles by this author Filip Ameye More articles by this author Simone Albisinni More articles by this author Peter Dekuyper More articles by this author David Jegou More articles by this author Thierry Quackels More articles by this author Thierry Roumeguere More articles by this author Ben Van Cleynenbreugel More articles by this author Nancy Van Damme More articles by this author Liesbet Van Eycken More articles by this author Steven Joniau More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...