Step-Efficient Access to Chiral Primary Amines
SYNTHESIS-STUTTGART(2013)
摘要
Routes to enantioenriched amines are outlined that employ reductive amination and carbanion addition methods. The strategies require either one or two reaction steps from prochiral carbonyl compounds for the synthesis of the corresponding chiral primary amines.
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关键词
chiral amine,enantiopure amines,reductive amination,cuprate addition,imine reduction
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