Requirement of argininosuccinate lyase for systemic nitric oxide production

NATURE MEDICINE, pp. 1619-U134, 2011.

Cited by: 73|Views14


Nitric oxide (NO) is crucial in diverse physiological and pathological processes. We show that a hypomorphic mouse model of argininosuccinate lyase (encoded by Asl) deficiency has a distinct phenotype of multiorgan dysfunction and NO deficiency. Loss of Asl in both humans and mice leads to reduced NO synthesis, owing to both decreased end...More



Get fulltext within 24h
Upload PDF

1.Your uploaded documents will be check within 24h, and coins will be credited to your account.

2.As the current system does not support cash withdrawal, you can add staff WeChat (AMxiaomai) to receive it as a red packet.

3.10 coins will be exchanged for 1 yuan.


Upload a single paper

for 5 coins

Wechat's Red Packet

Upload 50 articles

for 250 coins

Wechat's Red Packet

Upload 200 articles

for 1000 coins

Wechat's Red Packet

Upload 500 articles

for 2500 coins

Wechat's Red Packet

Upload 1000 articles

for 5000 coins

Wechat's Red Packet
Your rating :