Characteristic Expression Pattern of Hypoxia Inducible Factor 2 Alpha Mutation-Related Paragangliomas

Stephanie M. J. Fliedner,Uma Shankavaram,Abdel Elkahloun,Hendrik Lehnert,Karel Pacak

Experimental and clinical endocrinology & diabetes（2015）

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摘要

Within the last five years, the number of known mutated genes predisposing to paragangliomas (PGLs) has more than tripled. Strong genotype-phenotype associations have been recognized, indicating the need for individualized treatment approaches.

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