Culture Medium Geometry: The Dominant Factor Affecting In Vitro Rf Exposure Dosimetry

Biological experiments that expose living cells or tissues to RF energy must have an aqueous medium to provide essential water, ions, nutrients, and growth factors. However, as we show here, the medium inherently functions as a receiving antenna that conveys RF energy to the biological entity in a manner entirely determined by exposure vessel geometry, orientation to the incident RF flux, frequency, and dielectric properties of the medium. We show for two common experimental arrangements that basic antenna theory can predict electromagnetic energy patterns that agree well with those otherwise obtained by computationally intensive methods that require specialized resources.