OC03.05: Three‐dimensional ultrasound characterization of uterine junctional zone in patients with recurrent miscarriage: a new diagnostic tool?

established: failed PUL, intrauterine pregnancy (IUP) or ectopic pregnancy (EP). Univariate analysis was performed in order to establish the significant variables for the different PUL outcomes (ANOVA F-test and Fisher’s exact test). Results: 152/2067 (7.35%) women were initially classified as a PUL. 142/152 (93.4%) women were included in the final analysis. Final PUL outcomes were: 71.1% (101/142) failed PUL, 20.4% (29/142) IUP and 8.45% (12/142) EP. Endometrial symmetry data was available for 95.1% (135/142) women with a PUL at the initial TVS. Off-line analysis of 3-D TVS images showed a symmetric endometrial cavity for 55.2% (16/29) IUPs, 88.3% (83/94) failed PULs, and 91.7% (11/12) EPs. There was a significant association between endometrial symmetry (symmetric vs. asymmetric) and 3-category PUL outcome (P = 0.00017). Conclusions: The use of 3-D TVS in the evaluation of uterine cavity symmetry may be useful in the prediction of PUL outcome at the primary scan. In particular, the presence of an asymmetrical endometrial cavity seems to be most commonly associated with PULs that subsequently develop into intrauterine pregnancies.