Synthesis of novel zerumbone derivatives via regioselective palladium catalyzed decarboxylative coupling reaction: a new class of α-glucosidase inhibitors

K R Ajish,B P Dhanya,Nayana Joseph,M Priya Rani,K G Raghu,V P Vineetha,K V Radhakrishnan

Tetrahedron Letters（2014）

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摘要

•A new strategy for the synthesis of novel zerumbone derivatives.•First palladium catalyzed decarboxylative coupling reaction on zerumbone.•Most of the newly synthesized derivatives are α-glucosidase enzyme inhibitors.

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关键词

Zerumbone,Zingiber zerumbet,Palladium,Decarboxylative coupling,α-Glucosidase inhibitors

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