Pre-hospital metoprolol administration in Killip-class I–II anterior ST-segment elevation acute myocardial infarction is safe and reduces infarct size and adverse events. Insights from the METOCARD-CNIC trial

Alonso Mateos, Ines Garcia,J M Garcia,Juan Valenciano,Pilar Huertas,Jose Antonio Iglesias,M J Fernandez, R J Rodriguez Fernandez, Borja Ruiz,Jesus Bravo, A Garcia, Leticia Fernandez, Antonio Maestro Fernandez, A Alvarez Albarran,Andres Iniguez,Ervigio Corral,Carlos Macaya,Valentin Fuster,Vicente Martin Sanchez,Borja Ibanez

Resuscitation(2014)

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摘要
Objective: Pre-reperfusion administration of i.v. metoprolol has been shown to reduce infarct size in Killip-class I–II anterior ST-segment elevation myocardial infarction (STEMI) patients undergoing primary angioplasty (METOCARD-CNIC trial, Circulation 2013). The objective of the present study was to study the effects of i.v. metoprolol administration in the pre-hospital emergency care environment.
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关键词
acute myocardial infarction,myocardial infarction,infarction size,pre-hospital,killip-class,st-segment,metocard-cnic
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