Abnormal uterine bleeding in VTE patients treated with rivaroxaban compared to vitamin K antagonists

Nico De Crem,Kathelijne Peerlinck,Thomas Vanassche, Kristine Vanheule, Barbara Debaveye,S Middeldorp,Peter Verhamme,Marijke Peetermans

Thrombosis Research（2015）

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摘要

•Rivaroxaban offers convenient oral anticoagulation for patients with VTE.•Abnormal uterine bleeding (AUB) is frequent during anticoagulant therapy.•Treatment with rivaroxaban is associated with prolonged menstrual bleeding vs. VKA.•VTE patients on rivaroxaban (vs. VKA) report more medical interventions for AUB.•Strategies to mitigate AUB, e.g. continued oral contraceptive use, need further study.

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关键词

AUB,BMI,DVT,FIGO,IQR,LMWH,DOAC,PE,VKA,VTE

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