C0295 Measurement of Dabigatran and Rivaroxaban in Primary Prevention of Venous Thromboembolism in 106 Patients, Who Have Undergone Major Orthopedic Surgery. an Observational Study

No routine coagulation laboratory test is recommended during rivaroxaban or dabigatran treatment. However measuring drug concentration and/or anticoagulant activity can be desirable in some special clinical settings, such as bleeding, thrombosis recurrence oremergency surgery… The effects of dabigatran etexilate and rivaroxaban on various coagulation assays have been previously studied in normal plasma spiked with increasing concentrations of the drug. In contrast, few data are available in routinely treated patients.