Dynamics of epileptic activity in a peculiar case of childhood absence epilepsy and correlation with thalamic levels of GABA.

•A childhood absence epilepsy case with single hemispheric involvement is described.•Thalamic GABA/Cr ratio of affected versus reference hemisphere was increased to 2.57.•A similar ratio between occipital cortex ROIs was 1.09, which was within normal range.•We propose a role for increased thalamic GABA in childhood absence epilepsy.