Staphylococcal SCC mec elements encode an active MCM-like helicase and thus may be replicative

Ignacio Mir-Sanchis, Christina A Roman,Agnieszka Misiura,Ying Z Pigli, Susan Boyle-Vavra,Phoebe A Rice

NATURE STRUCTURAL & MOLECULAR BIOLOGY（2016）

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摘要

One of the conserved proteins of the Staphylococcus aureus mobile genomic island responsible for methicillin resistance is an active MCM-like helicase, thus suggesting replication that would enhance the efficiency of horizontal gene transfer.

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X-ray crystallography,Pathogens

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