Bacterial physiology: A new chaperone for regulatory sRNAs.

In bacteria, two RNA-binding proteins (RBPs) — Hfq and CsrA — are known to be global post-transcriptional regulators that chaperone small RNAs (sRNAs). However, numerous sRNAs do not associate with either of these chaperones, which raises the possibility that these sRNAs bind to RBPs that have as-yet-undiscovered global regulatory roles. Now, Smirnov et al. identify ProQ as a third sRNA ch… Download references