Identification and characterization of PPARα ligands in the hippocampus

Avik Roy,Madhuchhanda Kundu,Malabendu Jana,Rama K Mishra,Yeni Yung,Chi-Hao Luan,Frank J Gonzalez,Kalipada Pahan

Nature chemical biology（2016）

引用 14|浏览20

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摘要

Three endogenous ligands of the nuclear receptor PPARα—hydroxydimethylbutyrate, hexadecanamide, and octadecenamide—are potentially responsible for noncanonical activity of PPARα in synaptic function and hippocampal plasticity.

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关键词

Biochemistry,Cell signalling,Molecular neuroscience,Transcription,Chemistry/Food Science,general,Biochemical Engineering,Cell Biology,Bioorganic Chemistry

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