Genome and network visualization facilitates the analyses of the effects of drugs and mutations on protein-protein and drug-protein networks

BMC Bioinformatics(2016)

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摘要
Biologists generally interrogate genomics data using web-based genome browsers that have limited analytical potential. New generation genome browsers such as the Integrated Genome Browser (IGB) have largely overcome this limitation and permit customized analyses to be implemented using plugins. We illustrate the use of a plugin for IGB that exploits advanced visualization techniques to integrate the analysis of genomics data with network and structural approaches.
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关键词
Protein networks,Structures,Genome variants,Genome browsing,Visualization,Protein-protein interaction,Protein-ligand interactions
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