Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche

Yue Shao,Kenichiro Taniguchi,Katherine Gurdziel,Ryan F. Townshend,Xufeng Xue,Koh Meng Aw Yong,Jianming Sang,Jason R. Spence,Deborah L. Gumucio,Jianping Fu

NATURE MATERIALS（2016）

引用 153|浏览6

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摘要

The control of biophysical cues during the culture of human pluripotent stem cells on biomaterial substrates can be used to replicate the in vivo amniogenic environment and direct in vitro generation of early human amniotic tissue.

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关键词

Biomedical engineering,Stem-cell biotechnology,Biomaterials - cells,Stem-cell niche,Pluripotent stem cells

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