Hormone Replacement Therapy and the Cardiovascular System
Drugs(1994)
摘要
Coronary heart disease (CHD) is the leading cause of death in women, and the risk of this disease rises markedly after loss of ovarian function. Hormone replacement therapy (HRT) can reduce the incidence of CHD in postmenopausal women by 50%. HRT causes changes in lipids and lipoproteins, but it is now clear that many other effects of gonadal steroid hormones have important influences on the cardiovascular system. These nonlipid effects include a variety of changes in other metabolic risk factors for CHD, as well as direct arterial effects.
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关键词
Insulin Resistance,Hormone Replacement Therapy,Coronary Heart Disease Risk,Coronary Heart Disease Risk Factor,Dydrogesterone
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