The impact of a delayed consent model on trial recruitment - the cream study (children with eczema antibiotic management study)

Background The CREAM Study is a randomised controlled trial that aims to address the uncertainty around the effect of oral and topical antibiotics on subjective and objective eczema severity in children with clinically infected eczema in primary care. Children were identified by GPs and referred to local CREAM research nurses. Research nurses arranged a baseline visit to the participant’s home with 72 hours. Eligibility was re-confirmed at the visit and informed consent was obtained.