Objective Criteria for Septal Fibrosis in Non-Ischemic Dilated Cardiomyopathy: Validation for the Prediction of Future Cardiovascular Events

Expert subjective reporting of mid-wall septal fibrosis on late gadolinium enhancement (LGE) images has been shown to predict major cardiovascular outcomes in patients with non-ischemic dilated cardiomyopathy (NIDCM). This study aims to establish objective criteria for non-experts to report clinically relevant septal fibrosis and compare its performance by such readers versus experts for the prediction of cardiovascular events.