Autophagy-related protein expression was associated with BRAF V600E mutation in epilepsy associated glioneuronal tumors.
Epilepsy Research(2017)
摘要
•We are aiming to explore the expression level of autophagy-related proteins in epileptic patients with glioneuronal tumors (GNTs) and evaluate the association with clinicopathological features.•High expression of LC3B and Beclin-1 proteins was significantly associated with BRAF V600E mutation in GNTs.•Autophagy-related proteins did not show any association with other studied clinicopathological features, including postoperative seizure outcome.
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关键词
Autophagy-related protein,BRAF V600E,Epilepsy,Glioneuronal tumors
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