Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils

Shuo-yao Qu,Jia-Ji Lin,Jian Zhang,Li-Qiang Song,Xue-Min Yang,Chang-gui Wu

Cellular Immunology（2017）

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摘要

•Notch signaling regulated BA’s proliferation and apoptosis.•Notch signaling regulated BA’s cytokine secretion.•The regulation mechanisms were involved in JNK and ERK.

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关键词

APC,BA,CCK-8,DC,ERK,GSI,IL,JNK,MAPKs,TGF-β,PBS

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