Expression of the GluA2 subunit of glutamate receptors is required for the normal dendritic differentiation of cerebellar Purkinje cells.

Masahiko Tanaka, Tomomi Senda,Naohide Hirashima

Neuroscience Letters（2017）

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摘要

•Dendritic differentiation was inhibited by GluA2 knockdown in Purkinje cells.•[Ca2+]i elevation was augmented by GluA2 knockdown in Purkinje cells.•GluA2 inhibits the negative effect of excessive [Ca2+]i elevation in Purkinje cells.

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关键词

Purkinje cell,Dendrite,GluA2 (GluR2),AMPA receptor,Calcium,Single-cell electroporation

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