Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case.

Abigail B Diack,Aileen Boyle,Diane Ritchie,Chris Plinston,Dorothy Kisielewski,Jesús de Pedro-Cuesta,Alberto Rábano,Robert G Will,Jean C Manson

EMERGING INFECTIOUS DISEASES（2017）

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摘要

We investigated transmission characteristics of variant Creutzfeldt-Jakob disease in a mother and son from Spain. Despite differences in patient age and disease manifestations, we found the same strain properties in these patients as in UK vCJD cases. A single strain of agent appears to be responsible for all vCJD cases to date.

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关键词

BSE,Spain,TSE,United Kingdom,mouse study,prions,strain,transmissible spongiform encephalopathy,vCJD,variant Creutzfeldt-Jakob disease

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