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Proteomic analysis of influenza haemagglutinin-specific antibodies following vaccination reveals convergent immunoglobulin variable region signatures.

Penelope J Adamson,Mahmood A Al Kindi,Jing J Wang,Alex D Colella,Timothy K Chataway,Nikolai Petrovsky,Tom P Gordon,David L Gordon

Vaccine（2017）

Cited 8|Views16
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Abstract
•Anti-H1 Igs were purified from sera following H1N1pdm09 influenza A vaccination.•Proteome of secreted anti-H1 Igs was analysed by mass spectrometric sequencing.•Anti-H1 Igs express convergent antibody response in unrelated individuals.
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Key words
IgV,rHA,H,L,D,J,K,IMGT,CDR,BCR,PBMC
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