Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice.

Carmen A Argmann,Sara Violante,Tetyana Dodatko,Mariana P Amaro,Jacob Hagen,Virginia L Gillespie,Christoph Buettner,Eric E Schadt,Sander M Houten

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease（2017）

引用 13|浏览32

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摘要

•Loss of KLF14 function does not affect diet-induced obesity phenotypes in male mice.•KLF14 expression is undetectable in adult mouse liver.•KLF14 is highly expressed in mouse adenohypophysis.•Loss of KLF14 function impacts on the pituitary transcriptome.

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BAT,DEG,FPLC,GWAS,HDL-C,HFD,IPGTT,KLF,KO,eQTL,TG,WAT

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