Local infusion of ghrelin into the lateral amygdala blocks extinction of conditioned taste aversion in rats.
Neuroscience Letters(2018)
摘要
•Intra-LA infusion of ghrelin blocks extinction of acquired CTA memory.•Intra-LA infusion of ghrelin blocks both extinction and acquisition through activation of the ghrelin receptor, GHS-R1a.•PI3K inhibitor only abolishes the suppression of ghrelin/GHS-R1a signaling on acquisition, but not on extinction.
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关键词
Ghrelin,GHS-R1a,CTA,Lateral amygdala,Memory extinction
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