Alternatively spliced fibronectin extra domain A is required for hemangiogenic recovery upon bone marrow chemotherapy.

Alessandro Malara,Cristian Gruppi, Giuseppe Celesti,Vittorio Abbonante,Gianluca Viarengo, Luigi Laghi,Luigi De Marco, Andrés F Muro,Alessandra Balduini

Haematologica（2017）

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摘要

In the bone marrow (BM), the hematopoietic stem cells (HSCs) give rise to all blood cell lineages.[1][1] The maintenance, differentiation and proliferation of HSCs are regulated in both cell-autonomous (e.g. GATA-1 or PU.1 transcription factors) and non-cell-autonomous ways. The non-cell-autonomous

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