Target Intestinal Microbiota to Alleviate Disease Progression in Amyotrophic Lateral Sclerosis.

Yong-Guo Zhang,Shaoping Wu,Jianxun Yi,Yinglin Xia,Dapeng Jin,Jingsong Zhou,Jun Sun

Journal of neurology & neuromedicine（2017）

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摘要

The findings from this study highlight the complex role of the gut microbiome and intestinal epithelium in the progression of ALS and present butyrate as a potential therapeutic reagent for restoring ALS-related dysbiosis.

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关键词

ALS,butyrate,dysbiosis,intestinal permeability,microbiome,tight junctions

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