Ambient surface mass spectrometry-ion mobility spectrometry of intact proteins.
Current Opinion in Chemical Biology(2018)
摘要
•Liquid microjunction surface-sampling techniques are suitable for analysis of intact proteins.•Liquid extraction surface analysis is a versatile technique for protein profiling.•High-field asymmetric waveform ion mobility affords improved S/N and molecular separation.•Molecular separation by ion mobility spectrometry is highly useful in mass spectrometry imaging.
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