Effects of exposure to water disinfection by-products in a swimming pool: A metabolome-wide association study.

Environment International(2018)

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摘要
•MWAS of exposure to Disinfection By-Products from swimming in a chlorinated pool•6471 metabolic features were detected by UHPLC-QTOF- Mass Spectrometry.•DBP exposures were measured in exhaled breath, urine and in swimming water.•293 metabolic features associated to at least one DPB, and 137 to all exposures•Annotation revealed 13 compounds involved in the tryptophan metabolism pathway.
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关键词
Disinfection by-products,DBPs,Metabolome,LC-MS,Blood,Exposome
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