Epitope Identification of Specific Naturally Occurring Human Anti-avidin Antibodies.

•Naturally occurring human anti-avidin IgG and immunized rabbit anti-avidin common epitopes were characterized and synthesized.•Such epitopes suggest promising applications in several fields of research and medicine. They may serve as.•Inhibitors preventing the rapid elimination of avidin from the circulatory system when administered for diagnostic or drug-delivery purposes.•Competitors that neutralize antibodies causing immunological adverse reactions.•Tools to study the function of “biologically redundant” anti-dietary IgG class antibodies in the serum of healthy and symptomatic individuals.