Comparative study for 147 Candida spp. identification and echinocandins susceptibility in isolates obtained from blood cultures in 15 hospitals, Medellin, Colombia.
Journal of Global Antimicrobial Resistance(2018)
摘要
•Overall agreement between MALDI-TOF/MS and molecular identification was 99.3%.•Susceptibility to anidulafungin and caspofungin by broth microdilution (BMD) was 98.0% and 88.4%, respectively.•Susceptibility to anidulafungin and caspofungin by Etest was 93.9% and 98.6%, respectively.•Agreement between BMD and Etest was 91.8% and 89.8% for anidulafungin and caspofungin, respectively.•No mutations leading to amino acid changes were found in the FKS gene(s) in Candida spp. isolates.
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关键词
Candidaemia,Candida,Echinocandin susceptibility,Molecular identification,MALDI-TOF/MS,FKS silent mutations
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