Isolated myelosarcoma is characterized by recurrent NFE2 mutations and concurrent preleukemic clones in the bone marrow.

Blood(2017)

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TO THE EDITOR:Myeloid (or granulocytic) sarcoma (MS), that is, an extramedullary tumor consisting of myeloid blastic cells, is a unique clinical presentation of any type of acute myeloid leukemia (AML), according to the World Health Organization.[1][1] It could present (1) de novo (isolated MS), (
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