Plasmodium falciparum Recrudescence Two Years after a First Treated Uncomplicated Infection without Return in a Malaria Endemic Area.

Denis Malvy,Marylin Torrentino-Madamet,Coralie L'Ollivier,Marie-Catherine Receveur,Fakhri Jeddi,Laurence Delhaes,Renaud Piarroux,Pascal Millet,Bruno Pradines

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY（2018）

引用 27|浏览16

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摘要

We report evidence, confirmed by the lack of travel activity outside of France and genetic diversity analysis using polymorphic microsatellite markers, that Plasmodium falciparum malaria infection effectively treated with an artemisinin-based combination can remain dormant and relapse during pregnancy at least 2 years after treatment.

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关键词

malaria,Plasmodium falciparum,antimalarial drug,resistance,in vitro,in vivo,molecular marker

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