Efficient purification of Apolipoprotein A1 (ApoA1) from plasma by HEA HyperCel™: An alternative approach.

Arun Govind G,Agamudi Shivasankaran Kamalanathan,Mookambeswaran Arunachalam Vijayalakshmi,Krishnan Venkataraman

Journal of Chromatography B（2018）

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摘要

•Plasma HDL-apoA1 is considered cardioprotective.•Conventional method of apoA1 purification involves tedious multiple steps.•An efficient method of apoA1 purification from blood plasma is demonstrated.•HEA HyperCel mixed mode resin has been exploited for purification.•Purified apoA1 is structurally intact and significantly pure.

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关键词

ApoA1,CVD,ESI,HEA,MEP,PPA,Q-ToF,Vcap

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