Structural Target Controllability of Linear Networks.

IEEE/ACM Transactions on Computational Biology and Bioinformatics(2018)

引用 27|浏览14
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摘要
Computational analysis of the structure of intra-cellular molecular interaction networks can suggest novel therapeutic approaches for systemic diseases like cancer. Recent research in the area of network science has shown that network control theory can be a powerful tool in the understanding and manipulation of such bio-medical networks. In 2011, Liu et al. developed a polynomial time algorithm c...
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关键词
Controllability,Drugs,Linear systems,Diseases,Optimization,Heuristic algorithms,Approximation algorithms
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